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This list contains some of the most useful and/or class defining items that will improve quality of life. Keep in mind not all clickies are included. Some are more useful than others. Get what works for you.
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Classic
Journeyman’s Boots
Run Speed Buff – Journeyman’s Boots Quest
Shield of the Immaculate
Cure Disease – PoHate – Lord of Ire (Classic-PoP), an eerie chest (LDoN+)
Warden Symbol of Tunare (CLR/DRU, HUM/ELF/HIE/HEF, Tunare Only)
Grasping Roots – North Felwithe Quest: Tunare Symbol Quests
Kunark
Bracer of the Hidden
Instant See invisible (can cast on others) – Lake of Ill Omen – a sarnak chancellor/a sarnak legionnaire. Rare.
Defender of the Faithful Heart
Primal Essence (+20 Melee Stats, can cast on level 1) – Quest – Dithgar’s Defender
Di`Zok Escape Staff
Evacuate – Chardok – an Alchemist`s Acolyte
Dragon Spine Staff
200 Magic DD – Veeshan’s Peak – Silverwing
Earring of Woven Bark
Snare – Chardok – Captain Di`ouz
Elder Spiritist Set (Kunark Class Set)
Various Clickes — See screenshot – Old Sebilis/Karnor’s Castle/Howling Stones
Fungi Covered Great Staff
Self-Regen – Old Sebilis – myconid spore king (nerfed version – select classes only)
Fungus Covered Great Staff
Self-Regen – Old Sebilis – myconid spore king (pre-nerf version – any class can click this) (King’s Court Casino Later – GoD)
Goblin Gazughi Ring
Invis vs. Animals – Lake of Ill Omen – a sarnak courier
Luminescent Staff
4 Target AE DD – Old Sebilis – Baron Yosig
Lycanthropic Staff
Form of the Great Wolf (Run Speed + Attack) – Karnor’s Castle – Venril Sathir
Nature Walkers Scimitar
DoT – Druid 1.0 Epic Quest
Ring of Stealthy Travel
Gather Shadows (Self-Invis) – Chardok – Interrogator Gi`mok
Shrunken Goblin Skull Earring
Instant Attack Buff – Warsliks Woods – Grachnist the Destroyer
Velious
Flowers of Functionality
+50 Resist – 1.0 Plane of Mischief Card Quest
Gloves of Earthcrafting
+24 DS Buff (Shield of Thorns) – PoGrowth Quest
Polymorph Wand: Forest Fairy
Levitate – Daybreak Store (Illusions) – 750 Points (shows up sometime between Velious and PoP)
Woven Grass Set
Various Clickes — See Screenshot – Velious Class Sets (Thurgadin, Skyshrine, Kael)
Luclin
Armguard of Piety
Abolish Poison – Vex Thal – Diabo Xi Va Temariel
Bracelet of the Shadow Hive
1 sec shrink (can cast on others) – Vex Thal – Diabo Xi Xin Thall
Bone Earring of Evasion
Invis vs. Undead – Vex Thal – Va Xi Aten Ha Ra
Circle of Smoke
Gate – Ssraeshza Temple – Vyzh`dra the Cursed
Crimson Ring of Judgment
+250 Max Mana (AA Grant) – Vex Thal – Aten Ha Ra
Elder’s Armbands of Ro
Attack/Fire Resist/AC Debuff – Vex Thal – Diabo Xi Va
Hoop of Emptiness
2x Dispel – Ssraeshza Temple – Arch Lich Rhag`Zadune
Gloves of Warding
+50 Magic Resist – Vex Thal – Thall Va Kelu
Jade Skull Ring
2x Dispel – Ssraeshza Temple – Arch Lich Rhag`Zadune/Vyzh`dra the Exiled
Ring of Immobilization
Root – Vex Thal – Diabo Xi Va
Ring of Resistance
+10 All Resists – Vex Thal – South Blob
Shadowed Storm Sphere
+3 Mana Regen/Rune – Akheva Ruins – Shei Vinitras
Shawl of Awakenings
+5 Mana Regen (AA Grant) – Ssraeshza Temple – Emperor Ssraeshza
Shroud of Emerald Vines
Counteract Poison – Ssraeshza Temple – High Priest of Ssraeshza
Sporecaller
DoT – Ssraeshza Temple – High Priest of Ssraeshza
Talisman of the Burrower
+2 Mana Regen (AA Grant) – Acrylia Caverns – an evolved burrower
Tanglewood Shield
Ensnare – Wakening Land – Woushi
Torque of the Wyrmlord
300 HP, 30 STAM, 20 CHA (Doesn’t stack with Brells/Strength of Tunare Line) – Ssraeshza Temple – Emperor Ssraeshza
Twilight Shroud
+2 Mana Regen (AA Grant) – Vex Thal – Diabo Xi Va
Wand of Imperceptibility
Self Shrink – The Deep – Koxiux the Imperceptible
Wistful Tunic of the Void
225 HP, 40 CR/MR Buff – Ssraeshza Temple – Vyzh`dra the Cursed
Xanthe’s Earring of Nature
Circle of the Combines (Dreadlands Portal) – Tradeskill Quest
Planes of Power
Bangle of Disease Warding
Resist Disease (Instant-cast) – PoDisease – Grimror Plaguebringer (CoD Alt Access Quest)
Blackflame Sphere
Remove Greater Curse – Plane of Fire – Pyronis
Blade of the Tempest
DoT – Halls of Honor B – Mithaniel Marr
Boots of the Mosquito
Invis vs. Animals – Temple of Cazic Thule 2.0 – a virulent mosquito
Celestial Cloak
+5 Mana Regen (AA Grant) – Plane of Time – Bertoxxulous
Earring of Celestial Energy
+20 All Resist (AA Grant) – PoTime – Innoruuk
Eye of Dreams
+400 Max Mana (AA Grant) – Plane of Time – Bertoxxulous
Kerasha’s Sylvan Leggings
Legacy of Bracken (Group DS) – PoP Ornate Elemental Gear
Orb of Clinging Death
DoT – PoTime – Terris Thule
Shawl of Eternal Forces
+8 Mana Regen (AA Grant) – Plane of Time – Quarm
Prismatic Ring of Resistance
AC/Resist Buff (AA Grant) – Plane of Time – Quarm
Shield of Coral
Evacuate – PoWater – Gigadon/Hammertooth/Razorfin/Swordfang
Shield of Striding
Instant Levitation (self-only) – Temple of Cazic-Thule 2.0 – an enraged disciple
Wand of the Vortex
Annul Magic (2x Dispel) – PoTime – Phase 2
Wanderer’s Sylvan Set (Ornate Gear)
Group Regen/Root – PoP Ornate Quest Gear
Lost Dungeons of Norrath
Steelslave Earthen Boots of Strategy
Flight of Eagles – LDoN Raid: Prison Break
Earring of Spirited Mind
+2 Mana Regen (AA Grant) – LDoN Raid: War March of Imal Ojun